Subramanian, Ravi

From MolEvol

Ravi Subramanian

Postdoctoral Associate, Tufts University

Boston, MA, USA

I study the role of endogenous retroviruses in human evolution as well as their role in breast and other cancers.

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About My Work

Human endogenous retroviruses (HERVs) result from viral infections in the germ line and constitute about 8% of the human genome. Examples of HERV-K expression, ranging from RNA transcripts to virus particles visible in electron micrographs, have been observed in mammary tumors. We are examining expression patterns in a set of breast cancer cell lines, as well as primary mammary epithelial and tumor cells to determine their role in breast cancer initiation or progression. We are also studying the pattern of integration of these viruses in human evolution.