Difference between revisions of "Nicholas Meyerson"

From MolEvol
 
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[[File:Nick2.jpg|350px|thumb|right|Oh you know... trying to cast a fireball spell at CSH Retroviruses 2012]]
 
[[File:Nick2.jpg|350px|thumb|right|Oh you know... trying to cast a fireball spell at CSH Retroviruses 2012]]
  
Postdoctoral Fellow and Lab Manager of the [[Sara_Sawyer|Sawyer Lab]]
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[[File:Evolution.png]]<br>
  
<b>nrmeyerson@gmail.com</b>
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*Postdoctoral Fellow and Project Manager of the [[Sara_Sawyer|Sawyer Lab at CU Boulder]]
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*<b>nrmeyerson@gmail.com</b>
  
 
I specialize in evolutionary analyses using PAML and downstream functional analyses using various molecular biology and biochemical tools. Feel free to talk to me during or after the course about your ideas/concerns/confusions.  
 
I specialize in evolutionary analyses using PAML and downstream functional analyses using various molecular biology and biochemical tools. Feel free to talk to me during or after the course about your ideas/concerns/confusions.  
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*Probing the fate of duplicated genes by constructing chimeras from deeply divergent species (i.e. fungi and archaea)
 
*Probing the fate of duplicated genes by constructing chimeras from deeply divergent species (i.e. fungi and archaea)
  
==Links==
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==Relevant Publications==
*[http://sawyerlab.colorado.edu/Sawyer_Lab_Website/Home.html The Sawyer Lab]
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*[https://molevol.mbl.edu/images/4/4b/Two-stepping.pdf Two-stepping through time: mammals and viruses]
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*[https://molevol.mbl.edu/images/4/41/Positive_Selection_of_Primate_Genes.pdf Positive selection of primate genes that promote HIV-1 replication]
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*[https://molevol.mbl.edu/images/f/fa/Mol_Biol_Evol-2015-McBee-1091-6.pdf The effect of species representation on the detection of positive selection in primate gene data sets]
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*[https://molevol.mbl.edu/images/b/bb/Owl_monkey_CD4_paper.pdf Identification of owl monkey CD4 receptors broadly compatible with early-stage HIV-1 isolates]
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==Resources==
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*[http://sawyerlab.colorado.edu/Sawyer_Lab_Website/Home.html The Sawyer Lab at CU Boulder]
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*[http://www.datamonkey.org Datamonkey] - an online resource that implements several different programs that detect positive selection
  
*[http://www.sciencedirect.com/science/article/pii/S0966842X11000540 Two stepping through time: mammals and viruses]
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*[http://www.bork.embl.de/pal2nal/ Pal2Nal] - a protein alignment-guided codon alignment program. Useful for generating PAML-ready alignment files
  
*[https://molevol.mbl.edu/wiki/images/f/f8/PAMLtreetutorial.pdf A tutorial on editing tree files for branch isolation in PAML]
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*[https://molevol.mbl.edu/images/e/ed/PAML_tree_tutorial.pdf A tutorial on editing tree files for branch isolation in PAML]

Latest revision as of 19:30, 24 July 2017

MolEvol2011: Experimenting with bathroom luminescence with Conor and Emily during our first year in the course
Oh you know... trying to cast a fireball spell at CSH Retroviruses 2012

Evolution.png

  • nrmeyerson@gmail.com

I specialize in evolutionary analyses using PAML and downstream functional analyses using various molecular biology and biochemical tools. Feel free to talk to me during or after the course about your ideas/concerns/confusions.

Research Interests

  • Understanding the evolutionary trajectory of primate genes involved in host-virus interactions
  • Functionally characterizing the consequences of rapidly evolving codons during viral replication using mammalian tissue culture
  • Ancestral state reconstruction of primate genes involved in the cross-species transmission of retroviruses to functionally test their role as barriers to zoonosis
  • Discovering novel antiviral restriction factors in primates using PAML positive selection analysis
  • Probing the fate of duplicated genes by constructing chimeras from deeply divergent species (i.e. fungi and archaea)

Relevant Publications

Resources

  • Datamonkey - an online resource that implements several different programs that detect positive selection
  • Pal2Nal - a protein alignment-guided codon alignment program. Useful for generating PAML-ready alignment files